Infecção experimental de Lutzomyia whitmani em cães infectados com Leishmania braziliensis braziliensis

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Immunity to Lutzomyia whitmani Saliva Protects against Experimental Leishmania braziliensis Infection

BACKGROUND Previous works showed that immunization with saliva from Lutzomyia intermedia, a vector of Leishmania braziliensis, does not protect against experimental infection. However, L. braziliensis is also transmitted by Lutzomyia whitmani, a sand fly species closely related to Lu. intermedia. Herein we describe the immune response following immunization with Lu. whitmani saliva and the outc...

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Clinical and hematological findings in Leishmania braziliensis-infected dogs from Pernambuco, Brazil Achados clínicos e hematológicos em cães infectados por Leishmania braziliensis de Pernambuco, Brasil

Canine cutaneous leishmaniasis by Leishmania braziliensis is a neglected, but widespread disease of dogs in South America. This paper describes clinical and hematological alterations in 17 L. braziliensis-infected dogs from Brazil. The most common hematological findings were thrombocytopenia (82.4%), anemia (70.6%), low packed cell volume (52.9%) and eosinophilia (41.2%). Twelve (70.6%) dogs di...

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Differential Midgut Attachment of Leishmania (Viannia) braziliensis in the Sand Flies Lutzomyia (Nyssomyia) whitmani and Lutzomyia (Nyssomyia) intermedia

The interaction between Leishmania and sand flies has been demonstrated in many Old and New World species. Besides the morphological differentiation from procyclic to infective metacyclic promastigotes, the parasite undergoes biochemical transformations in its major surface lipophosphoglycan (LPG). An upregulation of beta-glucose residues was previously shown in the LPG repeat units from procyc...

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Effect of Lutzomyia whitmani (Diptera: Psychodidae) salivary gland lysates on Leishmania (Viannia) braziliensis infection in BALB/c mice.

Previous reports showed that Lutzomyia longipalpis saliva exacerbate Leishmania braziliensis infection in mice. The sand fly Lu. whitmani is one of the vectors of L. (Viannia) braziliensis (LVb), a causative agent of cutaneous leishmaniasis in the State of Ceará, Brazil. To determine whether saliva of Lu. whitmani could increase the infectivity of LVb in mice, we inoculated groups of BALB/c mic...

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The Vectorial Potential of Lutzomyia (Nyssomyia) intermedia and Lutzomyia (N.) whitmani in the Transmission of Leishmania (V.) braziliensis Can Also Be Related to Proteins Attaching

We read with great interest the report by Soares et al. [1] on the potential of Leishmania (Viannia) braziliensis to attach to the midgut of the sand flies Lutzomyia (N.) whitmani and Lutzomyia (N.) intermedia. This manuscript assesses relevant information concerning the biomolecular phenomena between Leishmania promastigotes and the midgut of Lutzomyia species that act as vectors of American C...

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ژورنال

عنوان ژورنال: Memórias do Instituto Oswaldo Cruz

سال: 1986

ISSN: 0074-0276

DOI: 10.1590/s0074-02761986000100017